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Multifunctional role of Nobiletin in cancer chemoprevention
Multifunctional role of Nobiletin in cancer chemoprevention
Institute of Pharmaceutical Sciences, PUMHSW, Nawabshah, Pakistan
Rukset Attar
Department of Obstetrics and Gynecology, Yeditepe University, Turkey
Ulku Ozbey
Department of Nutrition and Dietetics, Faculty of Health Sciences, Munzur University, Turkey
Mirna Azalea Romero
Facultad de Medicina, Universidad Autónoma de Guerrero, Laboratorio de Investigación Clínica, Av. Solidaridad S/N, Colonia Hornos Insurgentes, cp 39300, Acapulco, Guerrero México
Ishmuratova Margarita Yulaevna
E. A. Buketov Karaganda University, Kazakhstan
Jelena Purenovic
Faculty of Technical Sciences, Cacak University of Kragujevac, Cacak, Serbia
Corresponding Author(s) : Rukset Attar
ruksetattar@hotmail.com
Cellular and Molecular Biology,
Vol. 68 No. 7: Issue 7
The diversity of highly bioactive and pharmacologically active natural products which recognize essential biological targets having exquisite specificity, constitutes a massive pharmacological database for discovery of valuable drugs. The rapid accumulation of information has revealed chemopreventive role of nobiletin against wide variety of cancers. Recent efforts are now being expanded and new integrative omics technologies have illuminated continuously upgrading list of molecular mechanisms which underlie carcinogenesis and metastasis. In this mini-review, we explore the progress that has been made in the identification of promising molecular targets of nobiletin.
Keywords
Cancerapoptosisanimal modelscell Signaling
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Malik, D.-E.-S. ., Attar, R. ., Ozbey, U. ., Romero, M. A. ., Yulaevna, I. M. ., & Purenovic, J. . (2022). Multifunctional role of Nobiletin in cancer chemoprevention: Multifunctional role of Nobiletin in cancer chemoprevention. Cellular and Molecular Biology, 68(7), 200–207. https://doi.org/10.14715/cmb/2022.68.7.33
