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Vol. 63 No. 10: Issue 10

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Ziziphus Jujube: a review study of its anticancer effects in various tumor models invitro and invivo

https://doi.org/10.14715/cmb/2017.63.10.19
S. Ebrahimi
Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran
H. Mollaei
Cellular & Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
R. Hoshyar
Cellular & Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran

Corresponding Author(s) : R. Hoshyar

reyhaneh.houshyar@gmail.com

Cellular and Molecular Biology, Vol. 63 No. 10: Issue 10

Abstract

The growing rate of cancer incidences and inefficiency of current therapies have made scientists to find novel agents such as medicinal plants. Ziziphus jujube is one of these plants whose pharmaceutical effects have been studied for a long time. Recent investigations have proved that bioactive compounds of Ziziphus jujube including triterpenic acids, flavonoids, cerebrosides, phenolic acids, α tocopherol, β carotene, and polysaccharides have anti-proliferative effects on several cancerous cell lines and animals. The present study aimed to cover all previous invitro and invivo findings and some of molecular mechanisms of its anticancer property.

Keywords

Ziziphus jujube Cancer Invivo Invitro Molecular mechanism IC50.
Ebrahimi, S., Mollaei, H., & Hoshyar, R. (2017). Ziziphus Jujube: a review study of its anticancer effects in various tumor models invitro and invivo. Cellular and Molecular Biology, 63(10), 122–127. https://doi.org/10.14715/cmb/2017.63.10.19
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