Issue
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.
Beneficial effects of deep sea fish oil on diabetic mice neurological injury
Corresponding Author(s) : Q. Niu
niuqxa@yeah.net
Cellular and Molecular Biology,
Vol. 63 No. 1: Issue 1
Abstract
Deep sea fish oil mainly includes polyunsaturated fatty acid, which is usually used as health products and applied for prevention of cardiovascular and cerebrovascular diseases. However, there are only a few studies investigating the diabetes induced nerve injury till now. We established the diabetic model by using the 8-week old inbred male mice, and assumed that fish oil had a certain therapeutic effect on related neurosensory impairment and oxidative stress. Mice were divided into group A (diabetic mice induced by streptozotocin (STZ) and treated with fish oil), group B (diabetic mice) and group C (normal mice, without STZ treatment). The memory and exploration ability were evaluated and oxidation status of brain tissue was detected. Results indicated that memory and exploration ability of fish oil group A was significantly improved compared to diabetic group B (P<0.05), and equal to group C. The malondialdehyde (MDA) level of fish oil group A was decreased significantly and antioxidant level was increased significantly compared to diabetic group B (P<0.05), and equal to group C. In conclusion, deep sea fish oil could be used as auxiliary health care products, which plays important role in preventing and treating implications of nerve lesion impairment induced by diabetes mellitus.
Keywords
Deep sea fish oil
Diabetes mellitus
Nervous lesion.
Qiao, Z., Chen, Y., Zhang, Y., & Niu, Q. (2017). Beneficial effects of deep sea fish oil on diabetic mice neurological injury. Cellular and Molecular Biology, 63(1), 45–48. https://doi.org/10.14715/cmb/2017.63.1.9
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
