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Copyright (c) 2024 See-Hyoung Park
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.Anti-wrinkle activity of the ethanol extract of Aronia melanocarpa for development of the cosmeceutical ingredients
Corresponding Author(s) : See-Hyoung Park
Cellular and Molecular Biology,
Vol. 70 No. 11: Issue 11
Abstract
Despite the abundance of natural biological resources in Aronia melanocarpa, there is still insufficient research specifically exploring the potential for developing cosmeceutical compositions utilizing this plant. To develop the ingredient with the cosmeceutical function, the anti-wrinkle effect of the ethanol extract of A. melanocarpa was investigated. The ethanol extract was prepared from the dried A. melanocarpa. DPPH radical scavenging activity was significantly increased by the ethanol extract of A. melanocarpa. Cell viability on CCD986Sk human fibroblast was not affected by the ethanol extract of A. melanocarpa. Moreover, the ethanol extract of A. melanocarpa demonstrated inhibition of both collagenase and elastase enzymes. Analysis through ELISA and western blotting revealed an elevation in collagen expression levels in CCD986Sk human fibroblasts treated with ethanol extract. Additionally, the extract induced migration and invasion in HaCaT human keratinocytes, potentially associated with the activation of tight junctions. These results offer insights for the development of innovative cosmeceutical formulations utilizing A. melanocarpa extract.
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