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Copyright (c) 2022 Hanxun Xu, Wenhai Zhao, Yimin Zhou, Li Zhang
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.Multi-omics in Spinal Cord Injury: Diagnosis, Prognosis, and Treatment
Corresponding Author(s) : Li Zhang
Cellular and Molecular Biology,
Vol. 68 No. 11: Issue 11
Abstract
A spinal cord injury (SCI) can result in varying degrees of limb movement impairment and sensory impairment, affecting the quality of life severely. The study of the molecular mechanisms underlying SCI disease has advanced greatly. However, there is still room for improvement in terms of the cognitive and systematic approaches used for disease diagnosis, progression, treatment, and prognosis. This situation might change as multi-omics technology advances. Single omics technology has some limitations when it comes to fully comprehending the disease progression pattern and directing SCI treatment. Therefore, a thorough understanding of the state of the art in omics research on SCI can explain the pathogenesis and mechanism of the disease and offer new, multifaceted treatments for SCI. This article reviews recent developments in the application of various omics techniques to diseases associated with SCI and discusses the advantages and disadvantages of using these techniques for disease diagnosis, prognosis, and treatment.
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