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Copyright (c) 2022 Elahe Tahmasebi, Ali Kaboudanian Ardestani, Zahra Hassani, Mostafa Alam, Kamyar Abbasi, Sepehr Kahrizi, Negar Madihi, Zahra Abbasi Parashkouh, Arman Mohammadi, Pooria Shahab, Danial Khayatan, Mohsen Yazdanian
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.The current novel drug delivery system (natural and chemical composites) in dental infections for antibiotics resistance: a narrative review
Corresponding Author(s) : Elahe Tahmasebi
Cellular and Molecular Biology,
Vol. 68 No. 10: Issue 10
Abstract
A mouth infection can also affect the teeth, the mouth tissues, and any other areas involved in the mouth. Biofilms formed by bacteria are the primary cause of mouth infections and other infectious diseases caused by bacteria. The most common dental problem is an infection or disease within the mouth. The term chronic infection is sometimes used to describe this type of problem. There is also the possibility that these discomforts may occur due to the presence of bacteria in plaque, which is responsible for causing inflammation throughout the body as a result of bacterial infection in the mouth. In many cases, antibiotics serve as a first-line treatment for mouth infections, especially those caused by bacteria, most commonly treated by antibiotics. It is common for antibiotics to be used orally, and they are absorbed into the body through their metabolism in the liver and kidneys. Antibiotic resistance, which is primarily caused by misuse and overuse of antibiotics, is also one of the most significant public health crises of the 21st century. With the help of new drug delivery systems, antibacterial resistance can be decreased in humans to maintain the effectiveness of antibiotics when they are used more frequently. By directly delivering antibiotics to damaged tissues and reducing undesirable side effects when administered systemically, antibiotic delivery systems enhance the efficiency of antibiotics in specific zones. Furthermore, several new delivery systems are being explored in an attempt to improve pharmacokinetics and pharmacodynamics, reduce bacterial resistance, and decrease dose times. As a result, antibiotics were delivered to tissues and biological fluids using an innovative delivery system. Research on some of the most prevalent dental diseases provides updates on antibiotic delivery systems that reduce antibiotic resistance. This review overviews oral infectious diseases, antibiotics effects, and the different delivery systems of these therapeutic approaches.
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