The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.
Veronica persica Poir. extract – antibacterial, antifungal and scolicidal activities, and inhibitory potential on acetylcholinesterase, tyrosinase, lipoxygenase and xanthine oxidase
Corresponding Author(s) : Mehdi Sharifi-Rad
mehdi_sharifirad@yahoo.com
Cellular and Molecular Biology,
Vol. 64 No. 8: Biosynthesis, metabolism and biological activities of natural products from medicinal and food plants
Abstract
Veronica persica (Persian speedwell) is a flowering plant local to Eurasia. In this study, several analyses were done to discover the antimicrobial and scolicidal activities and acetyl cholinesterase (AChE), tyrosinase (TYR), lipoxygenase (LOX), and xanthine oxidase (XO) inhibitory activities of V. persica extract. The results presented that B. subtilis was the most susceptible to the extract (MIC = 40.3 μg/mL), while P. aeruginosa was the most resistant strain (MIC = 250.9 μg/mL) among all bacteria evaluated. The extracts demonstrated significant activity versus E. granulosus (P < 0.5) with dose-dependent inhibitions of the protoscolices. The analyzed plant extract exhibited a high AChE and TYR inhibitory activity 55.3% and 52.7% (at the highest utilized dose – 3 mg/mL), respectively. The extract also showed high anti-inflammatory activities in analyses tested. Our research proposed that extract of this plant could be promising to the human health, markedly in the infectious, neurodegenerative and inflammatory disorders.
Keywords
Plantaginaceae
Antimicrobial activity
neuroprotective ativity
Anti-inflammatory activity
Antioxidant activity.
Sharifi-Rad, J., Tayeboon, G. S., Niknam, F., Sharifi-Rad, M., Mohajeri, M., Salehi, B., Iriti, M., & Sharifi-Rad, M. (2018). Veronica persica Poir. extract – antibacterial, antifungal and scolicidal activities, and inhibitory potential on acetylcholinesterase, tyrosinase, lipoxygenase and xanthine oxidase. Cellular and Molecular Biology, 64(8), 50–56. https://doi.org/10.14715/cmb/2018.64.8.8
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
