Type 2 diabetes and mental disorders; a plausible link with inflammation

B. Hajebrahimi; A. Kiamanesh; A. A. Asgharnejad Farid; G. Asadikaram

doi:10.14715/cmb/2016.62.13.13

Issue

Vol. 62 No. 13: Issue 13

Issue Published : December 27, 2016

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Type 2 diabetes and mental disorders; a plausible link with inflammation

https://doi.org/10.14715/cmb/2016.62.13.13

B. Hajebrahimi

Dept. of Psychology, Faculty of Humanity, Science and Research Branch, Islamic Azad University, Tehran, Iran

A. Kiamanesh

Dept. of Psychology, Faculty of Humanity, Science and Research Branch, Islamic Azad University, Tehran, Iran

A. A. Asgharnejad Farid

Mental Health Research Center, Department of Clinical Psychology, Tehran Institute of Psychiatry, Iran University of Medical Sciences, Tehran, Iran

G. Asadikaram

Neuroscience Research Center, Institute of Neuropharmacology Kerman University of Medical Sciences, Kerman, Iran

Corresponding Author(s) : A. Kiamanesh

a.kiamanesh@srbiau.ac.ir

Cellular and Molecular Biology, Vol. 62 No. 13: Issue 13
Article Published : November 30, 2016

Abstract

Mental disorders including depression and anxiety are the prevalent human diseases which are associated with several metabolic and non-metabolic diseases. Recent investigations demonstrated that the mental disorders can be considered as the potential inducers/stimulators of chronic inflammation. Based on the fact that chronic inflammation is a main cause of human diseases, hence, a hypothesis has been raised to explore the interaction between mental disorders and inflammation related metabolic diseases. Type 2 diabetes (T2D), as a complicated metabolic disorder, is associated with inflammation and also mental disorders. Accordingly, it has been hypothesized that depression and anxiety, as mental disorders may be the inducers/stimulators of inflammation in the patients suffering from T2D. This review article collected recent information regarding the roles of mental disorders on the chronic inflammation in the T2D patients.

Keywords

Type 2 diabetes Depression Anxiety Inflammation.

Hajebrahimi, B., Kiamanesh, A., Asgharnejad Farid, A. A., & Asadikaram, G. (2016). Type 2 diabetes and mental disorders; a plausible link with inflammation. Cellular and Molecular Biology, 62(13), 71–77. https://doi.org/10.14715/cmb/2016.62.13.13