Issue
Copyright (c) 2022 Yue Jiang
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.Changes of serum Se selectin, ACTH, LPS and SIRT1 levels in patients with acute pancreatitis and their correlation with disease severity
Corresponding Author(s) : Yue Jiang
Cellular and Molecular Biology,
Vol. 68 No. 9: Issue 9
Abstract
This experiment was designed to explore the changes in serum Se selectin, ACTH, LPS and SIRT1 levels in patients with acute pancreatitis and their correlation with the severity of the disease. To do this research, from March 2019 to December 2020, 86 patients with different degrees of acute pancreatitis were selected as the research object. They were divided into mild acute pancreatitis (MAP) group (n = 43), moderately severe acute pancreatitis and severe acute pancreatitis (MSAP + SAP) group (n = 43) and healthy group (n = 43). At the same time, the serum levels of Se selectin, ACTH, LPS and SIRT1 were detected after hospitalization. Results showed that the levels of serum Se selectin, ACTH and SIRT1 in the MAP group and MSAP + SAP group were lower than those in the healthy group; The LPS of the MAP group and MSAP + SAP group were higher than that of the healthy group. The results showed that serum Se selectin, ACTH and SIRT1 decreased with the development of the disease, showing a negative correlation; The change of LPS in patients will increase with the development of the disease, showing a positive correlation. Serum Se selectin, ACTH, SIRT1, and LPS can be used as diagnostic criteria and indicators of acute pancreatitis to achieve early prevention and treatment and improve the prognosis and quality of life of patients.
Keywords
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
