Issue

Vol. 64 No. 15: Issue 15

The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.

Antifungal activity of the essential oils of some medicinal plants against human and plant fungal pathogens

https://doi.org/10.14715/cmb/2017.64.15.3
Hamzeh Mafakheri
Researcher at AJA University of Medical Sciences, Tehran, Iran
Sayid Mahdi Mirghazanfari
Department of Physiology and Persian Medicine, School of Medicine, AJA University of Medical Sciences, Tehran, Iran

Corresponding Author(s) : Sayid Mahdi Mirghazanfari

smmirghazanfari@gmail.com

Cellular and Molecular Biology, Vol. 64 No. 15: Issue 15

Abstract

The present study was conducted to assess the antifungal activity of essential oils of medicinal plants Mentha piperita (peppermint), Foeniculum vulgare, Satureja hortensis (Savory), Ferula asafoetida and Cuminum cyminum against Alternaria sp., Bipolaris sorokiniana and Acremonium sclerotigenum. The antifungal activity was evaluated by Broth Microdilution Method. Minimum Inhibitory Concentration (MICs) and Minimum Fungicidal Concentration (MFCs) of the essential oils were compared with Amphotricin B and Captan as standard drug. MIC values for all essential oils were between 1 to 8 mg/mL. MIC value of Fennel essential oil was comparable to MFC value obtained from fungicide Captan. Peppermint essential oil exhibited maximum inhibitory and fungicide activity in concentrations of 2 mg/ml and 4 mg/ml against Alternaria sp. The essential oil was more effective than Fennel against Bipolaris, but MFC values of both essential oils were 4 mg/ml. C. cyminum displayed less susceptibility against all of the fungi. Regarding our finding, peppermint and Fennel oil seem to be a promising solution to control plant diseases.

Keywords

Foeniculum vulgare Satureja hortensis Ferula asafoetida Cuminum cyminum Captan Fungicide effect Traditional iranian medicine.
Mafakheri, H., & Mirghazanfari, S. M. (2018). Antifungal activity of the essential oils of some medicinal plants against human and plant fungal pathogens. Cellular and Molecular Biology, 64(15), 13–19. https://doi.org/10.14715/cmb/2017.64.15.3
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. Al-Sadi AM. Impact of plant diseases on human health. International Journal of Nutrition, Pharmacology, Neurological Diseases 2017; 7(2), 21.
  2. Gladieux P, Byrnes EJ, Aguileta G, Fisher MC, Heitman J, Giraud T. Epidemiology and evolution of fungal pathogens in plants and animals. In Genetics and Evolution of infectious disease 2011; (pp. 59-132).
  3. Zain ME. Impact of mycotoxins on humans and animals. Journal of Saudi Chemical Society 2011; 15(2), 129-144.
  4. Gauthier GM, Keller NP.Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans. Fungal genetics and biology 2013; 61, 146-157.
  5. Shuping DSS, Eloff JN. The use of plants to protect plants and food against fungal pathogens: A review. African Journal of Traditional, Complementary, and Alternative Medicines 2017; 14(4), 120.
  6. Stamatis N, Hela D, Konstantinou I. Occurrence and removal of fungicides in municipal sewage treatment plant. Journal of Hazardous Materials 2010; 175(1-3), 829-835.
  7. Neela FA, Sonia IA , Shamsi S. Antifungal activity of selected medicinal plant extract on Fusarium oxysporum Schlechtthe causal agent of fusarium wilt disease in tomato. American Journal of Plant Sciences 2014; 5(18), 2665.
  8. Mirghazanfari SM. Assay of pharmacological features of phoenix Dactylifera in the view of traditional and modern medicine. Life Science Journal 2013;10(7s).
  9. Asadi MS, Mirghazanfari SM, Dadpay M, Nassireslami E. Evaluation of wound healing activities of pomegranate (Punica granatum-Lythraceae) peel and pulp. Journal of Research in Medical and Dental Science 2018; 6(3), 230-236.
  10. Bakkali F, Averbeck S, Averbeck D, Idaomar M. Biological effects of essential oils: A review. Food and Chemical Toxicology 2008; (46), 446-475.
  11. Rasooli I, Gachkar L, Yadegarinia D, Bagher Rezaei M, Alipoor Astaneh S. Antibacterial and antioxidative characterisation of essential oils from Mentha piperita and Mentha spicata grown in Iran. Acta alimentaria 2007; 37(1), 41-52.
  12. Van Vuuren SF, Suliman S, Viljoen AM. The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. Letters in applied microbiology 2009; 48(4), 440-446.
  13. Samarasekera R, Weerasinghe IS, Hemalal KP. Insecticidal activity of menthol derivatives against mosquitoes. Pest Management Science: formerly Pesticide Science 2008; 64(3), 290-295.
  14. Ansari MA, Vasudevan P, Tandon, M, Razdan RK. Larvicidal and mosquito repellent action of peppermint (Mentha piperita) oil. Bioresource technology 2000; 71(3), 267-271.
  15. Matan N, Woraprayote W, Saengkrajang W, Sirisombat N, Matan N. Durability of rubberwood (Hevea brasiliensis) treated with peppermint oil, eucalyptus oil, and their main components. International Biodeterioration & Biodegradation 2009; 63(5), 621-625.
  16. Sokovic M, Marin PD, Brkic D, van Griensven LJ. Chemical composition and antibacterial activity of essential oils against human pathogenic bacteria. Food 2008; 1(2), 220-226.
  17. Zargari A Medicinal plants 1990. Tehran: Tehran 1. University Press
  18. Åžahin F, Karaman I, Güllüce M, í–ğütçü H, Åžengül M, Adıgüzel A, Kotan R. Evaluation of antimicrobial activities of Satureja hortensis L. Journal of ethnopharmacology 2003; 87(1), 61-65.
  19. Soylu S, Yigitbas H, Soylu EM, Kurt Åž. Antifungal effects of essential oils from oregano and fennel on Sclerotinia sclerotiorum. Journal of applied microbiology 2007; 103(4), 1021-1030.
  20. Gulfraz M, Mehmood S, Minhas N, Jabeen N, Kausar R, Jabeen K, Arshad G. Composition and antimicrobial properties of essential oil of Foeniculum vulgare. African Journal of Biotechnology 2008; 7(24).
  21. Mirghazanfari SM, Hosseinzadeh L, Shokoohinia Y, Aslany M, Kamali-Nejad M. Acute and subchronic toxicological evaluation of Echinophora platyloba DC (Apiaceae) total extract in Wistar rats. Clinics 2012; 67(5), 497-502.
  22. Kalantar M, Azimzadeh M, Sabour M, Vahidi A, Haghiroalsadat F, Sharafadini M. The Indigenous Cuminum Cyminum L. of Yazd Province; Chemical Assessment and Evaluation of its Antioxidant Effects. Journal of Shahid Sadoughi University of Medical Sciences 2011; 19(4), 472-481.
  23. Iacobellis NS, Lo Cantore P, Capasso F, Senatore F. Antibacterial activity of Cuminum cyminum L. and Carum carvi L. essential oils. Journal of agricultural and food chemistry 2005; 53(1), 57-61.
  24. Samadi N, Shahani S, Akbarzadeh H, Mohammadi MS , Safaripour E , Farjadmand F , Khanavi M. Essential oil analysis and antibacterial activity of Ferula asafetida L. aerial parts from Neishabour mountains 2016.
  25. Fincher RM, Fisher JF, Lovell RD, Newman CL, Espinel-Ingroff A, Shadomy, HJ. Infection due to the fungus Acremonium (cephalosporium). Medicine 1991;70(6), 398-409.
  26. Domsch KH, Gams W, Anderson TH. Compendium of soil fungi. IHW-Verlag and Verlagsbuchhandlung, Eching, Germany , 2007; 627 pp.
  27. Asgari B, Zare R, Payghami E. Hyphomycetous fungal community of barley phylloplane in East Azerbaijan province with emphasis on new taxa for Iranian fungal flora. Rostaniha 2004; 5(2): 67-70. 28Li et al., 2014.
  28. Li BH, Wang, CC, Dong XL, Zhang ZF, Wang CX. Acremonium brown spot, a new disease caused by Acremonium sclerotigenum on bagged apple fruit in China. Plant Dis 2014; 98: 1012.
  29. El Khizzi N, Bakheshwain S, Parvez S. Bipolaris: a plant pathogen causing human infections: an emerging problem in Saudi Arabia. Res J Microbiol 2010; 5(3), 212-7.
  30. Lawrence DP, Gannibal PB, Peever TL, Pryor BM. The sections of Alternaria: formalizing species-group concepts. Mycologia 2013; 105(3), 530-546.
  31. Adams RP, Sparkman OD. Review of Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. J Am Soc Mass Spectrom 2007; 18, 803-806.
  32. Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of yeasts 2008; Approved Standard-Third Edition M27-A3, 28.
  33. Dellavalle PD, Cabrera A, Alem D, Larrañaga P, Ferreira F, Dalla Rizza M. Antifungal activity of medicinal plant extracts against phytopathogenic fungus Alternaria spp. Chilean Journal of Agricultural Research 2011; 71(2), 231.
  34. Mohammadi A, Nazari H, Imani S, Amrollahi H. Antifungal activities and chemical composition of some medicinal plants. Journal de Mycologie Médicale/Journal of Medical Mycology 2014;24(2), e1-e8.
  35. Dellavalle PD, et al. Antifungal activity of medicinal plant extracts against phytopathogenic fungus Alternaria spp. Chilean Journal of Agricultural Research 2011; 71.2: 231.
  36. Sokovic M, Marin PD, Brkic D, van Griensven LJ . Chemical composition and antibacterial activity of essential oils against human pathogenic bacteria. Food 2008; 1(2), 220-226.
  37. Ezzat SM. In vitro inhibition of Candida albicans growth by plant extracts and essential oils.World Journal of Microbiology and Biotechnology 2001; vol. 17, no. 7, pp. 757–759.
  38. Tyagi AK, Malik A . Liquid and vapour-phase antifungal activities of selected essential oils against Candida albicans: microscopic observations and chemical characterization of cymbopogon citratus. BMC Complementary and Alternative Medicine 2010; vol. 10, article 65, 2010.
  39. Izadi Z, Esna-Ashari M, Ahmadvand G, Davoodi P, Piri K. Chemical Composition and Antibacterial Activity of the Essence oil of Peppermint (Mentha piperita L) . Armaghane danesh 2009; 14 (3) :45-54
  40. Abdolmaleki M, Bahraminejad S, Salari M, Abbasi S, Panjeke N. Antifungal activity of Peppermint (Mentha piperita L.) on Phytopathogenic Fungi. JMP 2011; 2 (38) :26-34 .
  41. Freire MM, Jham GN, Dhingra OD, Jardim CM, Barcelos RC, Valente VMM. Composition, antifungal activity and main fungitoxic components of the essential oil of Mentha piperita L. Journal of Food Safety 2012; 32(1), 29-36.
  42. Trombetta D, Castelli F, Sarpietro MG, Venuti V, Cristani M, Daniele C, Bisignano, G. Mechanisms of antibacterial action of three monoterpenes. Antimicrobial agents and chemotherapy 2005; 49(6), 2474-2478.
  43. Duarte MCT, Figueira GM, Sartoratto A, Rehder VLG, Delarmelina C. Anti-Candida activity of Brazilian medicinal plants. Journal of ethnopharmacology 2005; 97(2), 305-311.
  44. Pedrotti C, Ribeiro RT, Schwambach J. Control of Postharvest Fungal Rots on Grapes Using Essential Oil of Foeniculum vulgare Mill. Journal of Agricultural Science 2017; 9(4), 205.
  45. Mahmoudi E. Antifungal Effects of Foeniculum vulgare Mill. Herb Essential Oil on the Phenotypical Characterizations of Alternaria alternata Kessel. Journal of Essential Oil Bearing Plants 2017; 20(2), 583-590.
  46. Pradhanang PM, Momol MT, Olson SM, Jones JB. Effects of plant essential oils on Ralstonia solanacearum population density and bacterial wilt incidence in tomato. Plant disease 2003; 87(4), 423-427.
  47. Soylu S, Yigitbas H, Soylu EM, Kurt Åž. Antifungal effects of essential oils from oregano and fennel on Sclerotinia sclerotiorum. Journal of applied microbiology 2007; 103(4), 1021-1030.
  48. Mimica"Dukić N, Kujundžić S, Soković M, Couladis M. Essential oil composition and antifungal activity of Foeniculum vulgare Mill. obtained by different distillation conditions. Phytotherapy Research 2003; 17(4), 368-371. 2003.
  49. Dobrikov GM, Valcheva V, Nikolova Y, Ugrinova I, Pasheva E, Dimitrov V. Enantiopure antituberculosis candidates synthesized from (-)-fenchone. European journal of medicinal chemistry 2014; 77, 243-247.
  50. Yazdanpanah L, Mohamadi N. Antifungal activity of Satureja hortensis L. essential oil against Alternaria citri. European Journal of Experimental Biology 2014; 4(1), 399-403.
  51. Mihajilov-Krstev T, Radnović D, Kitić D, Stojanović-Radić Z, Zlatković B. Antimicrobial activity of Satureja hortensis L. essential oil against pathogenic microbial strains. Archives of Biological Sciences 2010; 62(1), 159-166.
  52. Boyraz N, í–zcan, M. Inhibition of phytopathogenic fungi by essential oil, hydrosol, ground material and extract of summer savory (Satureja hortensis L.) growing wild in Turkey. International journal of food microbiology, 2006; 107(3), 238-242.
  53. Najib Zade, Yadegari MH, Naghdi Badi H. Evaluation antifungal effects of essential oils Satureja khuzestanica and Myrtus communis. Presented for the M.Sc, Tarbiat Modares university, Tehran, 2009; (Persian).
  54. Haghighi F, Roudbar Mohammadi S, Soleimani N, Sattari M. Evaluation of antifungal activity of essential oils of Thymus vulgaris, Petroselinum Crispum, Cuminum cyminum and Bunium persicum on candida albicans in comparison with Fluconazole. Pathobiology Research 2011; 14(1), 29-35.
  55. Khosravi AR, Minooeianhaghighi MH, Shokri H, Emami SA, Alavi SM, Asili J. The potential inhibitory effect of Cuminum cyminum, Ziziphora clinopodioides and Nigella sativa essential oils on the growth of Aspergillus fumigatus and Aspergillus flavus. Brazilian Journal of Microbiology 2011; 42(1), 216-224.
  56. Zargari A. Handbook of Medical Plants .University of Tehran Press, Iran. 1997. (In Persian)
Read More
Author biographies is not available.
Crossref
Scopus
Google Scholar
Europe PMC
Download this PDF file
PDF
Statistic
Read Counter : 1312 Download : 642