Maslinic acid as an effective anticancer agent

Xiukun Lin; Ulku Ozbey; Uteuliyev Yerzhan Sabitaliyevich; Rukset Attar; Beraat Ozcelik; Yuanyan Zhang; Mingyue Guo; Minghua Liu; Saleh S Alhewairini; Ammad Ahmad Farooqi

doi:10.14715/cmb/2018.64.10.14

Issue

Vol. 64 No. 10: Issue 10

Issue Published : August 3, 2018

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Maslinic acid as an effective anticancer agent

https://doi.org/10.14715/cmb/2018.64.10.14

Xiukun Lin

Department of Pharmacology, Southwest Medical Univerisity, Luzhou, Sichuan 646000, China

Ulku Ozbey

Department of Genetics, Health High School, Munzur University, 62000, Tunceli, Turkey

Uteuliyev Yerzhan Sabitaliyevich

Kazakhstan Medical University "KSPH", Kazakhstan

Rukset Attar

Department of Obstetrics and Gynecology, Yeditepe University, Turkey

Beraat Ozcelik

Food Engineering Department, Istanbul Technical University, Maslak, 34469, Istanbul, Turkey

Yuanyan Zhang

Department of Pharmacology, Southwest Medical Univerisity, Luzhou, Sichuan 646000, China

Mingyue Guo

Department of Pharmacology, Southwest Medical Univerisity, Luzhou, Sichuan 646000, China

Minghua Liu

Department of Pharmacology, Southwest Medical Univerisity, Luzhou, Sichuan 646000, China

Saleh S Alhewairini

Department of Plant Production and Protection, College of Agriculture and Veterinary Medicine, Qassim University, P.O. Box 6622, Buraidah 51452, Al-Qassim, Saudi Arabia

Ammad Ahmad Farooqi

Institute of Biomedical and genetic Engineering (IBGE), Islamabad, Pakistan

Corresponding Author(s) : Ammad Ahmad Farooqi

ammadfarooqi@rlmclahore.com

Cellular and Molecular Biology, Vol. 64 No. 10: Issue 10
Article Published : July 30, 2018

Abstract

Maslinic acid (2Î±,3Î²-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.

Keywords

Cancer Signaling Apoptosis Maslinic Acid.

Lin, X., Ozbey, U., Sabitaliyevich, U. Y., Attar, R., Ozcelik, B., Zhang, Y., Guo, M., Liu, M., Alhewairini, S. S., & Farooqi, A. A. (2018). Maslinic acid as an effective anticancer agent. Cellular and Molecular Biology, 64(10), 87–91. https://doi.org/10.14715/cmb/2018.64.10.14