Call for Papers

Call for Papers

Steviol Glycosides Biosynthesis Pathway

Nowadays, especially in modern day societies, sugar consumption has dramatically been increased and this issue is associated with various health problems such as obesity, hyperglycemia, tooth decay and blood pressure. One of the prompt and proper solutions to tackle this problem is promoting natural sweeteners consumption.
Stevia rebaudiana Bertoni is one of 154 members of the genus Stevia and one of only two species that produce sweet steviol glycosides. The sweetness of the stevia leaves is caused by eight glycosides contained within them. These glycosides are stevioside, rebaudioside A, C, D, E, and F, steviolbioside, and dulcoside A. There are various genes that they are involved in different steps of Steviol glycosides biosynthesis pathway. The final step is governed by three UGTs (UDP-glycosyltransferases) including UGT85C2, UGT74G1 and UGT76G1. Other genes such as KS and KO were effective in previous steps of the pathway.
As the most suitable way to stevia propagation is tissue culture, investigation of various culture media factors impacts on the key genes of steviol glycoside biosynthesis pathway expression. Besides the gene expression, different morphological traits had been measured. Also, as the main aspect of studies about stevia is increasing steviol glycosides accumulation, the amount of two important ones, stevioside and rebaudioside A, had been determined in the in-vitro situation. These studies can help to stevia tissue culture optimization and will finally enhance a number of steviol glycosides accumulation in stevia leaves to produce high-quality natural sweeteners.

Guest Editor

Danial Kahrizi, Razi University, Iran dkahrizi@yahoo.com

Manuscript due: Monday, 7 August 2017

First Round of Reviews: Monday, 6 November 2017

Publication date: Monday, 25 December 2017


Advances in mechanism and treatment strategy of cancer

We invite investigators to contribute basic, translational and clinical studies, meta-analysis, as well as review articles that contribute towards understanding signaling mechanisms of tumor progression and metastasis, microenvironment, vasculogenic mimics/angiogenesis, identification of biomarkers for early diagnostics, clinical therapeutic approaches, and current concepts in the prevention and treatment of human cancer.

Potential topics include, but are not limited to the following:

  • Autophagy
  • Cancer progression
  • Cancer metastasis
  • Vasculogenic mimics/angiogenesis
  • Cancer microenvironment, such as extracellular matrix and exosome
  • Cancer survival
  • Chemotherapy resistance
  • Genetic polymorphisms
  • Non-coding RNA, such as miRNAs, lncRNAs and circRNAs
  • Radiosensitize
  • Vasculogenic mimicry

Guest Editor

Ye Zeng, Sichuan University, Chengdu, China yeQgzeng@gmail.com

Manuscript due: January 2018

First Round of reviews: February 2018

Publication date: April 2018


Special Issue on: Biosynthesis, metabolism and biological activities of natural products from medicinal and food plants

We invite investigators to submit both original research and review articles that explore all the aspects of bioactive phytochemicals, with emphasis on their functional roles on plant organisms. We are also interested in contributions focusing on biological and pharmacological activities of plant natural products, as well as on their roles in human nutrition as health-promoting agents.

Potential topics include, but are not limited to the following

  • Medicinal and food plants
  • Plant stress physiology
  • Plant secondary metabolites
  • Phytoalexins
  • Chemical ecology
  • Global climate changes
  • Environmental pollution
  • Functional foods
  • Nutraceuticals
  • Botanicals
  • Essential oils
  • Xenobiotic metabolism
  • Oral bioavailability

Guest Editor

Professor Marcello Iriti, Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, I-20133 Milan, Italy; marcello.iriti@unimi

Manuscript due: September 2017

First Round of reviews: December 2017

Publication date: February 2018


Submit your manuscripts to Professor Marcello Iriti.