@article{Salehi_Selamoglu_Sevindik_Fahmy_Al-Sayed_El-Shazly_Csupor-Löffler_Csupor_Yazdi_Sharifi-Rad_Arserim-Uçar_Arserim_Karazhan_Jahani_Dey_Azadi_Vakili_Sharopov_Martins_Büsselberg_2020, title={Achillea spp.: A comprehensive review on its ethnobotany, phytochemistry, phytopharmacology and industrial applications}, volume={66}, url={https://cellmolbiol.org/index.php/CMB/article/view/3710}, DOI={10.14715/cmb/2020.66.4.13}, abstractNote={The genus Achillea genus houses more than 100 species, a number of them are popularly used in traditional medicine for spasmodic gastrointestinal, gynecological and hepatobiliary disorders, hemorrhages, pneumonia, rheumatic pain, inflammation, wounds healing etc. Members of the genus contain a wide variety of volatile and non-volatile secondary metabolites, including terpenes, polyphenols, flavonoids and others. Multiple studies have assessed the biological effects and other aspects of Achillea spp. In a number of preclinical studies, Achillea plants and their essential oils have demonstrated promising antibacterial properties against a number of human and plant pathogens. Besides, the plants have displayed strong antioxidative and potent anti-proliferative and anticancer properties in various cellular and animal models. Achillea plants have widely been used as food preservative in food industry. Clinical studies have indicated its potential against multiple sclerosis (MS), irritable bowel syndrome (IBS), ulcerative colitis, episiotomy wound, primary dysmenorrhea, oral mucositis etc. The present work focuses to provide a brief overview on folk knowledge, phytochemistry, biological activity and applications of Achillea plants. There is a close relationship between the traditional ethnobotanical usage and pharmacological and clinical data from different Achillea spp. The application of Achillea plants and their extracts seems to be a promising alternative for antimicrobial and antioxidant purposes in food, pharmaceutical and cosmetic industries.}, number={4}, journal={Cellular and Molecular Biology}, author={Salehi, Bahare and Selamoglu, Zeliha and Sevindik, Mustafa and Fahmy, Nouran M. and Al-Sayed, Eman and El-Shazly, Mohamed and Csupor-Löffler, Boglárka and Csupor, DezsÅ‘ and Yazdi, Simin Emamzadeh and Sharifi-Rad, Javad and Arserim-Uçar, Dılhun Keriman and Arserim, Ender Hikmet and Karazhan, Natallia and Jahani, Ali and Dey, Abhijit and Azadi, Hamed and Vakili, Somayeh Afsah and Sharopov, Farukh and Martins, Natália and Büsselberg, Dietrich}, year={2020}, month={Jun.}, pages={78–103} }