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Vol. 66 No. 1: Issue 1

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Phytochemical screening of Moringa oleifera leaf extracts and their antimicrobial activities

https://doi.org/10.14715/cmb/2019.66.1.3
Gholamreza Bagheri
Department of Health, School of Health, Zabol University of Medical Sciences, Zabol, Iran
Miquel Martorell
Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepción, Concepción, Chile
Karina Ramí­rez-Alarcón
Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepción, Concepción, Chile
Bahare Salehi
Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran
Javad Sharifi-Rad
Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Corresponding Author(s) : Javad Sharifi-Rad

javad.sharifirad@gmail.com

Cellular and Molecular Biology, Vol. 66 No. 1: Issue 1

Abstract

Moringa oleifera is a tree native to tropical and subtropical regions of South India and used in traditional medicine. The aim of this study was characterize the phytochemicals present in M. oleifera leaf extracts and study their antimicrobial activities. Solvent extractions with Soxhlet apparatus of leaves were obtained using hexane, benzene, isopropanol, methanol, and water. The crude extracts were concentrated and screened for qualitative phytochemical analysis, and the antibacterial, antifungal and antiviral activities of crude extracts were measured by in vitro methods. Alkaloids, carbohydrates, tannins, phenolic compounds, terpenoids, cardiac glycosides, amino acids, oils and fats were found in the different crude extracts analyzed. Water and methanol extracts showed antibacterial activity against all selected bacteria, hexane and benzene extracts showed antifungal activity against all fungi tested, and hexane, benzene and isopropanol extracts showed activity against Hepatitis B virus. In conclusion, the leaves of M. oleifera have antimicrobial phytochemicals.

Keywords

Moringa oleifera Phytochemical Antimicrobial Antibacterial Antifungus.
Bagheri, G., Martorell, M., Ramí­rez-Alarcón, K., Salehi, B., & Sharifi-Rad, J. (2020). Phytochemical screening of Moringa oleifera leaf extracts and their antimicrobial activities. Cellular and Molecular Biology, 66(1), 20–26. https://doi.org/10.14715/cmb/2019.66.1.3
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